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A Chemical and Enzymatic Approach to Study Site-Specific Sumoylation
A variety of cellular pathways are regulated by protein modifications with ubiquitin-family proteins. SUMO, the Small Ubiquitin-like MOdifier, is covalently attached to lysine on target proteins via a cascade reaction catalyzed by E1, E2, and E3 enzymes. A major barrier to understanding the diverse...
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| Udgivet i: | PLoS One |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4669148/ https://ncbi.nlm.nih.gov/pubmed/26633173 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0143810 |
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