A Chemical and Enzymatic Approach to Study Site-Specific Sumoylation

A variety of cellular pathways are regulated by protein modifications with ubiquitin-family proteins. SUMO, the Small Ubiquitin-like MOdifier, is covalently attached to lysine on target proteins via a cascade reaction catalyzed by E1, E2, and E3 enzymes. A major barrier to understanding the diverse...

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Pubblicato in:PLoS One
Autori principali: Albuquerque, Claudio P., Yeung, Eyan, Ma, Shawn, Fu, Ting, Corbett, Kevin D., Zhou, Huilin
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2015
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4669148/
https://ncbi.nlm.nih.gov/pubmed/26633173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0143810
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