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Transcriptional regulation by miRNA mimics that target sequences downstream of gene termini()

Transcriptome studies have revealed that protein-coding loci within the human genome are overlapped at their 3′-termini by noncoding RNA (ncRNA) transcripts. Small duplex RNAs designed to be fully complementary to these 3′ ncRNAs can modulate transcription of the upstream gene. Robust regulation by...

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Bibliografske podrobnosti
izdano v:Mol Biosyst
Main Authors: Younger, Scott T., Corey, David R.
Format: Artigo
Jezik:Inglês
Izdano: 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4668949/
https://ncbi.nlm.nih.gov/pubmed/21589992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c1mb05090g
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