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Argonaute 2-dependent Regulation of Gene Expression by Single-stranded miRNA Mimics

MicroRNAs (miRNAs) are small noncoding transcripts that regulate gene expression. Aberrant expression of miRNAs can affect development of cancer and other diseases. Synthetic miRNA mimics can modulate gene expression and offer an approach to therapy. Inside cells, mature miRNAs are produced as doubl...

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Detalhes bibliográficos
Publicado no:Mol Ther
Main Authors: Matsui, Masayuki, Prakash, Thazha P, Corey, David R
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4881773/
https://ncbi.nlm.nih.gov/pubmed/26903376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2016.39
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