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A small molecule inhibitor for ATPase activity of Hsp70 and Hsc70 enhances the immune response to protein antigens

The ATPase activities of Hsp70 and Hsc70 are known to be responsible for regulation of various biological processes. However, little is known about the roles of Hsp70 and Hsc70 in modulation of immune responses to antigens. In the present study, we investigated the effect of apoptozole (Az), a small...

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Pubblicato in:Sci Rep
Autori principali: Baek, Kyung-Hwa, Zhang, Haiying, Lee, Bo Ryeong, Kwon, Young-Guen, Ha, Sang-Jun, Shin, Injae
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4668564/
https://ncbi.nlm.nih.gov/pubmed/26631605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep17642
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