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Hsp70 architecture: the formation of novel polymeric structures of Hsp70.1 and Hsc70 after proteotoxic stress.

Heat induces Hsp70.1 (HSPA1) and Hsc70 (HSPA8) to form complex detergent insoluble cytoplasmic and nuclear structures that are distinct from the cytoskeleton and internal cell membranes. These novel structures have not been observed by earlier immunofluorescence studies as they are obscured by the a...

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Bibliografische gegevens
Hoofdauteurs: Rohan Steel, Ryan S Cross, Sarah L Ellis, Robin L Anderson
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science (PLoS) 2012-01-01
Reeks:PLoS ONE
Online toegang:http://europepmc.org/articles/PMC3526589?pdf=render
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