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Naturally occurring isothiocyanates exert anticancer effects by inhibiting deubiquitinating enzymes

The anticancer properties of cruciferous vegetables are well known and attributed to an abundance of isothiocyanates (ITCs) such as benzyl ITC (BITC) and phenethyl ITC (PEITC). While many potential targets of ITCs have been proposed, a full understanding of the mechanisms underlying their anticancer...

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Pubblicato in:Cancer Res
Autori principali: Lawson, Ann P., Long, Marcus J. C., Coffey, Rory T., Qian, Yu, Weerapana, Eranthie, El Oualid, Farid, Hedstrom, Lizbeth
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4668232/
https://ncbi.nlm.nih.gov/pubmed/26542215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-15-1544
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