Release of amyloid beta-protein precursor derivatives by electrical depolarization of rat hippocampal slices.

Proteolytic processing of the beta-amyloid protein precursor (APP) is regulated by cell-surface receptors. To determine whether neurotransmitter release in response to neuronal activation regulates APP processing in brain, we electrically depolarized superfused rat hippocampal slices and measured so...

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Bibliografske podrobnosti
Main Authors: Nitsch, R M, Farber, S A, Growdon, J H, Wurtman, R J
Format: Artigo
Jezik:Inglês
Izdano: 1993
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC46681/
https://ncbi.nlm.nih.gov/pubmed/8506366
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