Differential Impact of LPG-and PG-Deficient Leishmania major Mutants on the Immune Response of Human Dendritic Cells

BACKGROUND: Leishmania major infection induces robust interleukin-12 (IL12) production in human dendritic cells (hDC), ultimately resulting in Th1-mediated immunity and clinical resolution. The surface of Leishmania parasites is covered in a dense glycocalyx consisting of primarily lipophosphoglycan...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:PLoS Negl Trop Dis
Main Authors: Favila, Michelle A., Geraci, Nicholas S., Jayakumar, Asha, Hickerson, Suzanne, Mostrom, Janet, Turco, Salvatore J., Beverley, Stephen M., McDowell, Mary Ann
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4667916/
https://ncbi.nlm.nih.gov/pubmed/26630499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0004238
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados