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Advances in receptor conformation research: the quest for functionally selective conformations focusing on the β (2)‐adrenoceptor
Seven‐transmembrane receptors, also called GPCRs, represent the largest class of drug targets. Upon ligand binding, a GPCR undergoes conformational rearrangement and thereby changes its interaction with effector proteins including the cognate G‐proteins and the multifunctional adaptor proteins, β‐ar...
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| Publicado no: | Br J Pharmacol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4667867/ https://ncbi.nlm.nih.gov/pubmed/25537131 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13049 |
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