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Stereocontrolled Synthesis of a Potential Transition-State Inhibitor of the Salicylate Synthase MbtI from Mycobacterium tuberculosis

[Image: see text] Mycobactins are small-molecule iron chelators (siderophores) produced by Mycobacterium tuberculosis (Mtb) for iron mobilization. The bifunctional salicylate synthase MbtI catalyzes the first step of mycobactin biosynthesis through the conversion of the primary metabolite chorismate...

詳細記述

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書誌詳細
出版年:J Org Chem
主要な著者: Liu, Zheng, Liu, Feng, Aldrich, Courtney C.
フォーマット: Artigo
言語:Inglês
出版事項: 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4667787/
https://ncbi.nlm.nih.gov/pubmed/26035083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.joc.5b00455
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