New Chromane-Based Derivatives as Inhibitors of Mycobacterium tuberculosis Salicylate Synthase (MbtI): Preliminary Biological Evaluation and Molecular Modeling Studies

Tuberculosis is the leading cause of death from a single infectious agent worldwide; therefore, the need for new antitubercular drugs is desperate. The recently validated target salicylate synthase MbtI is the first enzyme involved in the biosynthesis of mycobactins, compounds able to chelate iron,...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Pini, Elena, Poli, Giulio, Tuccinardi, Tiziano, Chiarelli, Laurent Roberto, Mori, Matteo, Gelain, Arianna, Costantino, Luca, Villa, Stefania, Meneghetti, Fiorella, Barlocco, Daniela
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6099841/
https://ncbi.nlm.nih.gov/pubmed/29933627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules23071506
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados