Cyclin dependent kinase 2 (CDK2) is a key mediator for EGF-induced cell transformation mediated through the ELK4/c-Fos signaling pathway

Cyclin dependent kinase 2 (CDK2) is a known regulator in the cell cycle control of the G1/S and S/G2 transitions. However, the role of CDK2 in tumorigenesis is controversial. Evidence from knockout mice as well as colon cancer cell lines indicated that CDK2 is dispensable for cell proliferation. In...

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Detalhes bibliográficos
Publicado no:Oncogene
Main Authors: Peng, Cong, Zeng, Weiqi, Su, Juan, Kuang, Yehong, He, Yijin, Zhao, Shuang, Zhang, Jianglin, Ma, Weiya, Bode, Ann M., Dong, Zigang, Chen, Xiang
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4666830/
https://ncbi.nlm.nih.gov/pubmed/26028036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2015.175
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