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Induction of c-fos expression through JNK-mediated TCF/Elk-1 phosphorylation.

Growth factors induce c-fos transcription by stimulating phosphorylation of transcription factor TCF/Elk-1, which binds to the serum response element (SRE). Under such conditions Elk-1 could be phosphorylated by the mitogen-activated protein kinases (MAPKs) ERK1 and ERK2. However, c-fos transcriptio...

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Autors principals: Cavigelli, M, Dolfi, F, Claret, F X, Karin, M
Format: Artigo
Idioma:Inglês
Publicat: 1995
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC394715/
https://ncbi.nlm.nih.gov/pubmed/8846788
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