FANCA safeguards interphase and mitosis during hematopoiesis in vivo

Fanconi anemia (FA/BRCA) signaling network controls multiple genome-housekeeping checkpoints, from interphase DNA repair to mitosis. The in vivo role of abnormal cell division in FA remains unknown. Here, we quantified the origins of genomic instability in FA patients and mice in vivo and ex vivo. W...

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Bibliographic Details
Published in:Exp Hematol
Main Authors: Abdul-Sater, Zahi, Cerabona, Donna, Sierra Potchanant, Elizabeth, Sun, Zejin, Enzor, Rikki, He, Ying, Robertson, Kent, Goebel, W. Scott, Nalepa, Grzegorz
Format: Artigo
Language:Inglês
Published: 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4666759/
https://ncbi.nlm.nih.gov/pubmed/26366677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exphem.2015.08.013
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