FANCA safeguards interphase and mitosis during hematopoiesis in vivo

Fanconi anemia (FA/BRCA) signaling network controls multiple genome-housekeeping checkpoints, from interphase DNA repair to mitosis. The in vivo role of abnormal cell division in FA remains unknown. Here, we quantified the origins of genomic instability in FA patients and mice in vivo and ex vivo. W...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Exp Hematol
Päätekijät: Abdul-Sater, Zahi, Cerabona, Donna, Sierra Potchanant, Elizabeth, Sun, Zejin, Enzor, Rikki, He, Ying, Robertson, Kent, Goebel, W. Scott, Nalepa, Grzegorz
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2015
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4666759/
https://ncbi.nlm.nih.gov/pubmed/26366677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exphem.2015.08.013
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