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The DNA methylation landscape of human melanoma
Using MIRA-seq, we have characterized the DNA methylome of metastatic melanoma and normal melanocytes. Individual tumors contained several thousand hypermethylated regions. We discovered 179 tumor-specific methylation peaks present in all (27/27) melanomas that may be effective disease biomarkers, a...
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| Pubblicato in: | Genomics |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4666751/ https://ncbi.nlm.nih.gov/pubmed/26384656 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ygeno.2015.09.004 |
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