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Defining Driver DNA Methylation Changes in Human Cancer
Human malignant tumors are characterized by pervasive changes in the patterns of DNA methylation. These changes include a globally hypomethylated tumor cell genome and the focal hypermethylation of numerous 5′-cytosine-phosphate-guanine-3′ (CpG) islands, many of them associated with gene promoters....
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| Publié dans: | Int J Mol Sci |
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| Auteur principal: | |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
MDPI
2018
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5979276/ https://ncbi.nlm.nih.gov/pubmed/29649096 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19041166 |
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