The SUMOylation Pathway Restricts Gene Transduction by Adeno-Associated Viruses

Adeno-associated viruses are members of the genus dependoviruses of the parvoviridae family. AAV vectors are considered promising vectors for gene therapy and genetic vaccination as they can be easily produced, are highly stable and non-pathogenic. Nevertheless, transduction of cells in vitro and in...

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Veröffentlicht in:PLoS Pathog
Hauptverfasser: Hölscher, Christina, Sonntag, Florian, Henrich, Katharina, Chen, Qingxin, Beneke, Jürgen, Matula, Petr, Rohr, Karl, Kaderali, Lars, Beil, Nina, Erfle, Holger, Kleinschmidt, Jürgen A., Müller, Martin
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2015
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4666624/
https://ncbi.nlm.nih.gov/pubmed/26625259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005281
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