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Sources of PCR-induced distortions in high-throughput sequencing data sets
PCR permits the exponential and sequence-specific amplification of DNA, even from minute starting quantities. PCR is a fundamental step in preparing DNA samples for high-throughput sequencing. However, there are errors associated with PCR-mediated amplification. Here we examine the effects of four i...
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| Pubblicato in: | Nucleic Acids Res |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4666380/ https://ncbi.nlm.nih.gov/pubmed/26187991 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv717 |
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