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Detection of differentially methylated regions from whole-genome bisulfite sequencing data without replicates

DNA methylation is an important epigenetic modification involved in many biological processes and diseases. Recent developments in whole genome bisulfite sequencing (WGBS) technology have enabled genome-wide measurements of DNA methylation at single base pair resolution. Many experiments have been c...

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Bibliographische Detailangaben
Veröffentlicht in:Nucleic Acids Res
Hauptverfasser: Wu, Hao, Xu, Tianlei, Feng, Hao, Chen, Li, Li, Ben, Yao, Bing, Qin, Zhaohui, Jin, Peng, Conneely, Karen N.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4666378/
https://ncbi.nlm.nih.gov/pubmed/26184873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv715
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