A robust potency assay highlights significant donor variation of human mesenchymal stem/progenitor cell immune modulatory capacity and extended radio-resistance

The inherent immunomodulatory capacity of mesenchymal stem/progenitor cells (MSPCs) encouraged initiation of multiple clinical trials. Release criteria for therapeutic MSPCs cover identity, purity and safety but appropriate potency assessment is often missing. Reports on functional heterogeneity of...

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Bibliografiske detaljer
Udgivet i:Stem Cell Res Ther
Main Authors: Ketterl, Nina, Brachtl, Gabriele, Schuh, Cornelia, Bieback, Karen, Schallmoser, Katharina, Reinisch, Andreas, Strunk, Dirk
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2015
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Method
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4666276/
https://ncbi.nlm.nih.gov/pubmed/26620155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-015-0233-8
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