A robust potency assay highlights significant donor variation of human mesenchymal stem/progenitor cell immune modulatory capacity and extended radio-resistance

The inherent immunomodulatory capacity of mesenchymal stem/progenitor cells (MSPCs) encouraged initiation of multiple clinical trials. Release criteria for therapeutic MSPCs cover identity, purity and safety but appropriate potency assessment is often missing. Reports on functional heterogeneity of...

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Detalhes bibliográficos
Publicado no:Stem Cell Res Ther
Main Authors: Ketterl, Nina, Brachtl, Gabriele, Schuh, Cornelia, Bieback, Karen, Schallmoser, Katharina, Reinisch, Andreas, Strunk, Dirk
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Method
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4666276/
https://ncbi.nlm.nih.gov/pubmed/26620155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-015-0233-8
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