A robust potency assay highlights significant donor variation of human mesenchymal stem/progenitor cell immune modulatory capacity and extended radio-resistance

The inherent immunomodulatory capacity of mesenchymal stem/progenitor cells (MSPCs) encouraged initiation of multiple clinical trials. Release criteria for therapeutic MSPCs cover identity, purity and safety but appropriate potency assessment is often missing. Reports on functional heterogeneity of...

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Publicat a:Stem Cell Res Ther
Autors principals: Ketterl, Nina, Brachtl, Gabriele, Schuh, Cornelia, Bieback, Karen, Schallmoser, Katharina, Reinisch, Andreas, Strunk, Dirk
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2015
Matèries:
Method
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4666276/
https://ncbi.nlm.nih.gov/pubmed/26620155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-015-0233-8
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