A robust potency assay highlights significant donor variation of human mesenchymal stem/progenitor cell immune modulatory capacity and extended radio-resistance

The inherent immunomodulatory capacity of mesenchymal stem/progenitor cells (MSPCs) encouraged initiation of multiple clinical trials. Release criteria for therapeutic MSPCs cover identity, purity and safety but appropriate potency assessment is often missing. Reports on functional heterogeneity of...

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Bibliografiset tiedot
Julkaisussa:Stem Cell Res Ther
Päätekijät: Ketterl, Nina, Brachtl, Gabriele, Schuh, Cornelia, Bieback, Karen, Schallmoser, Katharina, Reinisch, Andreas, Strunk, Dirk
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: BioMed Central 2015
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Method
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4666276/
https://ncbi.nlm.nih.gov/pubmed/26620155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-015-0233-8
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