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gp78 functions downstream of Hrd1 to promote degradation of misfolded proteins of the endoplasmic reticulum
Eukaryotic cells eliminate misfolded proteins from the endoplasmic reticulum (ER) via a conserved process termed ER-associated degradation (ERAD). Central regulators of the ERAD system are membrane-bound ubiquitin ligases, which are thought to channel misfolded proteins through the ER membrane durin...
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| Publicado en: | Mol Biol Cell |
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| Autores principales: | , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
The American Society for Cell Biology
2015
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4666138/ https://ncbi.nlm.nih.gov/pubmed/26424800 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E15-06-0354 |
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