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GGA3 mediates TrkA endocytic recycling to promote sustained Akt phosphorylation and cell survival

Although TrkA postendocytic sorting significantly influences neuronal cell survival and differentiation, the molecular mechanism underlying TrkA receptor sorting in the recycling or degradation pathways remains poorly understood. Here we demonstrate that Golgi-localized, γ adaptin-ear–containing ADP...

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Pubblicato in:Mol Biol Cell
Autori principali: Li, Xuezhi, Lavigne, Pierre, Lavoie, Christine
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Cell Biology 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4666136/
https://ncbi.nlm.nih.gov/pubmed/26446845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E15-02-0087
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