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Mitochondrial metabolism mediates oxidative stress and inflammation in fatty liver

Mitochondria are critical for respiration in all tissues; however, in liver, these organelles also accommodate high-capacity anaplerotic/cataplerotic pathways that are essential to gluconeogenesis and other biosynthetic activities. During nonalcoholic fatty liver disease (NAFLD), mitochondria also p...

詳細記述

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書誌詳細
出版年:J Clin Invest
主要な著者: Satapati, Santhosh, Kucejova, Blanka, Duarte, Joao A.G., Fletcher, Justin A., Reynolds, Lacy, Sunny, Nishanth E., He, Tianteng, Nair, L. Arya, Livingston, Kenneth, Fu, Xiaorong, Merritt, Matthew E., Sherry, A. Dean, Malloy, Craig R., Shelton, John M., Lambert, Jennifer, Parks, Elizabeth J., Corbin, Ian, Magnuson, Mark A., Browning, Jeffrey D., Burgess, Shawn C.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Clinical Investigation 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4665800/
https://ncbi.nlm.nih.gov/pubmed/26571396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI82204
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