Mitochondrial metabolism mediates oxidative stress and inflammation in fatty liver

Mitochondria are critical for respiration in all tissues; however, in liver, these organelles also accommodate high-capacity anaplerotic/cataplerotic pathways that are essential to gluconeogenesis and other biosynthetic activities. During nonalcoholic fatty liver disease (NAFLD), mitochondria also p...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Satapati, Santhosh, Kucejova, Blanka, Duarte, Joao A.G., Fletcher, Justin A., Reynolds, Lacy, Sunny, Nishanth E., He, Tianteng, Nair, L. Arya, Livingston, Kenneth, Fu, Xiaorong, Merritt, Matthew E., Sherry, A. Dean, Malloy, Craig R., Shelton, John M., Lambert, Jennifer, Parks, Elizabeth J., Corbin, Ian, Magnuson, Mark A., Browning, Jeffrey D., Burgess, Shawn C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4665800/
https://ncbi.nlm.nih.gov/pubmed/26571396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI82204
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