Saturated phosphatidic acids mediate saturated fatty acid–induced vascular calcification and lipotoxicity

Recent evidence indicates that saturated fatty acid–induced (SFA-induced) lipotoxicity contributes to the pathogenesis of cardiovascular and metabolic diseases; however, the molecular mechanisms that underlie SFA-induced lipotoxicity remain unclear. Here, we have shown that repression of stearoyl-Co...

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Veröffentlicht in:J Clin Invest
Hauptverfasser: Masuda, Masashi, Miyazaki-Anzai, Shinobu, Keenan, Audrey L., Okamura, Kayo, Kendrick, Jessica, Chonchol, Michel, Offermanns, Stefan, Ntambi, James M., Kuro-o, Makoto, Miyazaki, Makoto
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 2015
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4665795/
https://ncbi.nlm.nih.gov/pubmed/26517697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI82871
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