Inhibition of DNA-PKcs enhances radiosensitivity and increases the levels of ATM and ATR in NSCLC cells exposed to carbon ion irradiation

Non-small cell lung cancer (NSCLC) exhibits radioresistance to conventional rays, due to its DNA damage repair systems. NSCLC may potentially be sensitized to radiation treatment by reducing those factors that continuously enhance the repair of damaged DNA. In the present study, normal lung fibrobla...

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Enregistré dans:
Détails bibliographiques
Publié dans:Oncol Lett
Auteurs principaux: YANG, LINA, LIU, YUANYUAN, SUN, CHAO, YANG, XINRUI, YANG, ZHEN, RAN, JUNTAO, ZHANG, QIUNING, ZHANG, HONG, WANG, XINYU, WANG, XIAOHU
Format: Artigo
Langue:Inglês
Publié: D.A. Spandidos 2015
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Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4665689/
https://ncbi.nlm.nih.gov/pubmed/26722253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2015.3730
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