Inhibition of DNA-PKcs enhances radiosensitivity and increases the levels of ATM and ATR in NSCLC cells exposed to carbon ion irradiation

Non-small cell lung cancer (NSCLC) exhibits radioresistance to conventional rays, due to its DNA damage repair systems. NSCLC may potentially be sensitized to radiation treatment by reducing those factors that continuously enhance the repair of damaged DNA. In the present study, normal lung fibrobla...

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Bibliographic Details
Published in:Oncol Lett
Main Authors: YANG, LINA, LIU, YUANYUAN, SUN, CHAO, YANG, XINRUI, YANG, ZHEN, RAN, JUNTAO, ZHANG, QIUNING, ZHANG, HONG, WANG, XINYU, WANG, XIAOHU
Format: Artigo
Language:Inglês
Published: D.A. Spandidos 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4665689/
https://ncbi.nlm.nih.gov/pubmed/26722253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2015.3730
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