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TARGETED THERAPIES: Afatinib—new therapy option for EGFR-mutant lung cancer

On 15 July 2013, the FDA approved afatinib as a first-line treatment for patients with metastatic non-small-cell lung cancer whose tumours harbour exon 19 deletions or exon 21 (L858R) EGFR substitution mutations. We discuss three recent studies investigating afatinib in this molecular subset of pati...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nat Rev Clin Oncol
Prif Awduron: Yu, Helena A., Pao, William
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2013
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4665630/
https://ncbi.nlm.nih.gov/pubmed/23959269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrclinonc.2013.154
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