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Effect of the dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor NVP-BEZ235 against human Merkel cell carcinoma MKL-1 cells

Merkel cell carcinoma (MCC) is an aggressive skin cancer with an increasing incidence. Aberrant activation of the phosphatidylinositol-3-kinase (PI3K)/Akt/mammalian target of rapamycin (mTOR) pathway is common in human cancers and has been revealed to play an important function in cell proliferation...

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Dettagli Bibliografici
Pubblicato in:Oncol Lett
Autori principali: LIN, ZHENYU, MEI, HONG, FAN, JIQUAN, YIN, ZHONGYUAN, WU, GANG
Natura: Artigo
Lingua:Inglês
Pubblicazione: D.A. Spandidos 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4665364/
https://ncbi.nlm.nih.gov/pubmed/26788188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2015.3791
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