Wird geladen...

Autophagy inhibition enhances colorectal cancer apoptosis induced by dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor NVP-BEZ235

Phosphatidylinositol 3-kinase (PI3K)/mammalian target of rapamycin (mTOR) signaling pathway performs a central role in tumorigenesis and is constitutively activated in many malignancies. As a novel dual PI3K/mTOR inhibitor currently undergoing evaluation in a phase I/II clinical trial, NVP-BEZ235 in...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Oncol Lett
Hauptverfasser: YANG, XIAOYU, NIU, BINGXUAN, WANG, LIBO, CHEN, MEILING, KANG, XIAOCHUN, WANG, LUONAN, JI, YINGHUA, ZHONG, JIATENG
Format: Artigo
Sprache:Inglês
Veröffentlicht: D.A. Spandidos 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4906634/
https://ncbi.nlm.nih.gov/pubmed/27347108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2016.4590
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!