SORBS2 transcription is activated by telomere position effect–over long distance upon telomere shortening in muscle cells from patients with facioscapulohumeral dystrophy

DNA is organized into complex three-dimensional chromatin structures, but how this spatial organization regulates gene expression remains a central question. These DNA/chromatin looping structures can range in size from 10–20 kb (enhancers/repressors) to many megabases during intra- and inter-chromo...

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Vydáno v:Genome Res
Hlavní autoři: Robin, Jérôme D., Ludlow, Andrew T., Batten, Kimberly, Gaillard, Marie-Cécile, Stadler, Guido, Magdinier, Frédérique, Wright, Woodring E., Shay, Jerry W.
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 2015
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4665000/
https://ncbi.nlm.nih.gov/pubmed/26359233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.190660.115
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