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Acetylation of glucokinase regulatory protein decreases glucose metabolism by suppressing glucokinase activity
Glucokinase (GK), mainly expressed in the liver and pancreatic β-cells, is critical for maintaining glucose homeostasis. GK expression and kinase activity, respectively, are both modulated at the transcriptional and post-translational levels. Post-translationally, GK is regulated by binding the gluc...
Guardat en:
| Publicat a: | Sci Rep |
|---|---|
| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group
2015
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4664969/ https://ncbi.nlm.nih.gov/pubmed/26620281 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep17395 |
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