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Acetylation of glucokinase regulatory protein decreases glucose metabolism by suppressing glucokinase activity
Glucokinase (GK), mainly expressed in the liver and pancreatic β-cells, is critical for maintaining glucose homeostasis. GK expression and kinase activity, respectively, are both modulated at the transcriptional and post-translational levels. Post-translationally, GK is regulated by binding the gluc...
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| Gepubliceerd in: | Sci Rep |
|---|---|
| Hoofdauteurs: | , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Nature Publishing Group
2015
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4664969/ https://ncbi.nlm.nih.gov/pubmed/26620281 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep17395 |
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