The standalone aminopeptidase PepN catalyzes the maturation of blasticidin S from leucylblasticidin S

The peptidyl nucleoside blasticidin S (BS) isolated from Streptomyces griseochromogenes was the first non-mercurial fungicide used on a large scale to prevent rice blast. In the biosynthesis of BS, leucylblasticidin S (LBS) was suggested as the penultimate metabolite with 20-fold less inhibitory act...

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Publicado en:Sci Rep
Autores principales: Yu, Guiyang, Li, Li, Liu, Xiangyang, Liu, Guang, Deng, Zixin, Zabriskie, Mark T., Jiang, Ming, He, Xinyi
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2015
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4664946/
https://ncbi.nlm.nih.gov/pubmed/26621790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep17641
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