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Streptomyces lividans Blasticidin S Deaminase and Its Application in Engineering a Blasticidin S-Producing Strain for Ease of Genetic Manipulation

Blasticidin S is a peptidyl nucleoside antibiotic produced by Streptomyces griseochromogenes that exhibits strong fungicidal activity. To circumvent an effective DNA uptake barrier system in the native producer and investigate its biosynthesis in vivo, the blasticidin S biosynthetic gene cluster (bl...

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Detalhes bibliográficos
Main Authors: Li, Li, Wu, Jun, Deng, Zixin, Zabriskie, T. Mark, He, Xinyi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3623232/
https://ncbi.nlm.nih.gov/pubmed/23377931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.03254-12
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