Engineered Streptomyces lividans Strains for Optimal Identification and Expression of Cryptic Biosynthetic Gene Clusters

Streptomyces lividans is a suitable host for the heterologous expression of biosynthetic gene clusters (BGCs) from actinomycetes to discover “cryptic” secondary metabolites. To improve the heterologous expression of BGCs, herein we optimized S. lividans strain SBT5 via the stepwise integration of th...

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Detalles Bibliográficos
Publicado en:Front Microbiol
Main Authors: Peng, Qinying, Gao, Guixi, Lü, Jin, Long, Qingshan, Chen, Xuefei, Zhang, Fei, Xu, Min, Liu, Kai, Wang, Yemin, Deng, Zixin, Li, Zhiyong, Tao, Meifeng
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2018
Assuntos:
Microbiology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6295570/
https://ncbi.nlm.nih.gov/pubmed/30619133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2018.03042
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