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Identification and characterization of the biosynthetic gene cluster of polyoxypeptin A, a potent apoptosis inducer
BACKGROUND: Polyoxypeptin A was isolated from a culture broth of Streptomyces sp. MK498-98 F14, which has a potent apoptosis-inducing activity towards human pancreatic carcinoma AsPC-1 cells. Structurally, polyoxypeptin A is composed of a C(15) acyl side chain and a nineteen-membered cyclodepsipepti...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3943440/ https://ncbi.nlm.nih.gov/pubmed/24506891 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2180-14-30 |
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