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Saccharomyces cerevisiae Is Dependent on Vesicular Traffic between the Golgi Apparatus and the Vacuole When Inositolphosphorylceramide Synthase Aur1 Is Inactivated

Inositolphosphorylceramide (IPC) and its mannosylated derivatives are the only complex sphingolipids of yeast. Their synthesis can be reduced by aureobasidin A (AbA), which specifically inhibits the IPC synthase Aur1. AbA reportedly, by diminishing IPC levels, causes endoplasmic reticulum (ER) stres...

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Dades bibliogràfiques
Publicat a:Eukaryot Cell
Autors principals: Voynova, Natalia S., Roubaty, Carole, Vazquez, Hector M., Mallela, Shamroop K., Ejsing, Christer S., Conzelmann, Andreas
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4664882/
https://ncbi.nlm.nih.gov/pubmed/26432633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/EC.00117-15
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