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Saccharomyces cerevisiae Is Dependent on Vesicular Traffic between the Golgi Apparatus and the Vacuole When Inositolphosphorylceramide Synthase Aur1 Is Inactivated

Inositolphosphorylceramide (IPC) and its mannosylated derivatives are the only complex sphingolipids of yeast. Their synthesis can be reduced by aureobasidin A (AbA), which specifically inhibits the IPC synthase Aur1. AbA reportedly, by diminishing IPC levels, causes endoplasmic reticulum (ER) stres...

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Bibliografische gegevens
Gepubliceerd in:Eukaryot Cell
Hoofdauteurs: Voynova, Natalia S., Roubaty, Carole, Vazquez, Hector M., Mallela, Shamroop K., Ejsing, Christer S., Conzelmann, Andreas
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2015
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4664882/
https://ncbi.nlm.nih.gov/pubmed/26432633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/EC.00117-15
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