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Saccharomyces cerevisiae Is Dependent on Vesicular Traffic between the Golgi Apparatus and the Vacuole When Inositolphosphorylceramide Synthase Aur1 Is Inactivated

Inositolphosphorylceramide (IPC) and its mannosylated derivatives are the only complex sphingolipids of yeast. Their synthesis can be reduced by aureobasidin A (AbA), which specifically inhibits the IPC synthase Aur1. AbA reportedly, by diminishing IPC levels, causes endoplasmic reticulum (ER) stres...

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Detaylı Bibliyografya
Yayımlandı:Eukaryot Cell
Asıl Yazarlar: Voynova, Natalia S., Roubaty, Carole, Vazquez, Hector M., Mallela, Shamroop K., Ejsing, Christer S., Conzelmann, Andreas
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2015
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4664882/
https://ncbi.nlm.nih.gov/pubmed/26432633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/EC.00117-15
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