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Functions of Ceramide Synthase Paralogs YPR114w and YJR116w of Saccharomyces cerevisiae
Ceramide is synthesized in yeast by two redundant acyl-CoA dependent synthases, Lag1 and Lac1. In lag1∆ lac1∆ cells, free fatty acids and sphingoid bases are elevated, and ceramides are produced through the redundant alkaline ceramidases Ypc1 and Ydc1, working backwards. Even with all four of these...
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| Udgivet i: | PLoS One |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4713442/ https://ncbi.nlm.nih.gov/pubmed/26752183 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0145831 |
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