Autoantibodies against Cytochrome P450 Side-Chain Cleavage Enzyme in Dogs (Canis lupus familiaris) Affected with Hypoadrenocorticism (Addison’s Disease)

Canine hypoadrenocorticism likely arises from immune-mediated destruction of adrenocortical tissue, leading to glucocorticoid and mineralocorticoid deficiency. In humans with autoimmune Addison’s disease (AAD) or autoimmune polyendocrine syndrome (APS), circulating autoantibodies have been demonstra...

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Bibliografiska uppgifter
I publikationen:PLoS One
Huvudupphovsmän: Boag, Alisdair M., Christie, Michael R., McLaughlin, Kerry A., Syme, Harriet M., Graham, Peter, Catchpole, Brian
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2015
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4664467/
https://ncbi.nlm.nih.gov/pubmed/26618927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0143458
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