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Polymorphisms in the CTLA4 promoter sequence are associated with canine hypoadrenocorticism

BACKGROUND: Canine hypoadrenocorticism is an immune-mediated endocrinopathy that shares both clinical and pathophysiological similarities with Addison’s disease in humans. Several dog breeds are overrepresented in the disease population, suggesting that a genetic component is involved, although this...

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Bibliographic Details
Published in:Canine Med Genet
Main Authors: Boag, Alisdair M., Short, Andrea, Kennedy, Lorna J., Syme, Hattie, Graham, Peter A., Catchpole, Brian
Format: Artigo
Language:Inglês
Published: BioMed Central 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7371821/
https://ncbi.nlm.nih.gov/pubmed/32835228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40575-020-0081-4
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