Induction of interferon-λ contributes to TLR3 and RIG-I activation-mediated inhibition of herpes simplex virus type 2 replication in human cervical epithelial cells

STUDY HYPOTHESIS: Is it possible to immunologically activate human cervical epithelial cells to produce antiviral factors that inhibit herpes simplex virus type 2 (HSV-2) replication? STUDY FINDING: Our results indicate that human cervical epithelial cells possess a functional TLR3/RIG-I signaling s...

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Bibliographic Details
Published in:Mol Hum Reprod
Main Authors: Zhou, Li, Li, Jie-Liang, Zhou, Yu, Liu, Jin-Biao, Zhuang, Ke, Gao, Jian-Feng, Liu, Shi, Sang, Ming, Wu, Jian-Guo, Ho, Wen-Zhe
Format: Artigo
Language:Inglês
Published: Oxford University Press 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4664393/
https://ncbi.nlm.nih.gov/pubmed/26502803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molehr/gav058
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