Llwytho...

Allosteric N-WASP activation by an inter-SH3 domain linker in Nck

Actin filament networks assemble on cellular membranes in response to signals that locally activate neural Wiskott–Aldrich-syndrome protein (N-WASP) and the Arp2/3 complex. An inactive conformation of N-WASP is stabilized by intramolecular contacts between the GTPase binding domain (GBD) and the C h...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Proc Natl Acad Sci U S A
Prif Awduron: Okrut, Julia, Prakash, Sumit, Wu, Qiong, Kelly, Mark J. S., Taunton, Jack
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2015
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4664294/
https://ncbi.nlm.nih.gov/pubmed/26554011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1510876112
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!