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Conserved interdomain linker promotes phase separation of the multivalent adaptor protein Nck
The organization of membranes, the cytosol, and the nucleus of eukaryotic cells can be controlled through phase separation of lipids, proteins, and nucleic acids. Collective interactions of multivalent molecules mediated by modular binding domains can induce gelation and phase separation in several...
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| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2015
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4664304/ https://ncbi.nlm.nih.gov/pubmed/26553976 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1508778112 |
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