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The role of the linker between the SH2 domain and catalytic domain in the regulation and function of Src.
The crystal structures of the regulated Src and Hck tyrosine kinases show intramolecular interactions between the phosphorylated tail and the SH2 domain as well as between the SH3 domain, the SH2-catalytic domain linker (SH2-CD linker) and the catalytic domain. The relative contribution of these int...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
1997
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1170326/ https://ncbi.nlm.nih.gov/pubmed/9405355 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/16.24.7261 |
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