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Splicing Factor Prp8 Interacts With NES(AR) and Regulates Androgen Receptor in Prostate Cancer Cells

Androgen receptor (AR) plays a pivotal role in the development of primary as well as advanced castration-resistant prostate cancer. Previous work in our lab identified a novel nuclear export signal (NES) (NES(AR)) in AR ligand-binding domain essential for AR nucleocytoplasmic trafficking. By charact...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Mol Endocrinol
Hauptverfasser: Wang, Dan, Nguyen, Minh M., Masoodi, Khalid Z., Singh, Prabhpreet, Jing, Yifeng, O'Malley, Katherine, Dar, Javid A., Dhir, Rajiv, Wang, Zhou
Format: Artigo
Sprache:Inglês
Veröffentlicht: Endocrine Society 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4664230/
https://ncbi.nlm.nih.gov/pubmed/26371515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2015-1112
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