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Splicing Factor Prp8 Interacts With NES(AR) and Regulates Androgen Receptor in Prostate Cancer Cells

Androgen receptor (AR) plays a pivotal role in the development of primary as well as advanced castration-resistant prostate cancer. Previous work in our lab identified a novel nuclear export signal (NES) (NES(AR)) in AR ligand-binding domain essential for AR nucleocytoplasmic trafficking. By charact...

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Detalhes bibliográficos
Publicado no:Mol Endocrinol
Main Authors: Wang, Dan, Nguyen, Minh M., Masoodi, Khalid Z., Singh, Prabhpreet, Jing, Yifeng, O'Malley, Katherine, Dar, Javid A., Dhir, Rajiv, Wang, Zhou
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4664230/
https://ncbi.nlm.nih.gov/pubmed/26371515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2015-1112
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